Cardioprotective therapeutics--drugs used in hypertension, hyperlipidaemia, thromboembolization, arrhythmias, postmenopausal state and as anti-oxidants.

Cardioprotective therapeutics--drugs used in hypertension, hyperlipidaemia, thromboembolism, arrhythmias, the postmenopausal state and as anti-oxidants.

Review of Anti-inflammatory and Immunosuppressive Drugs Used in COVID-19 Epidemic

Introduction: Immunosuppressive drugs are classified into different groups depending on the mechanism of action and are used in the control of acute and chronic inflammatory disorders. Considering the possibility of severe inflammatory complications such as acute respiratory failure and cytokine storm in the patients with COVID-19, there is a need to review the updated data on the effectiveness...

New evidence in hypertension and hyperlipidaemia.

The benefits of blood pressure lowering on the risk of cardiovascular disease are seen with all commonly used classes of antihypertensive drugs. Although different drug classes may have different effects on cause specific outcomes (such as myocardial infarction or stroke), no differences are observed between their overall effects on combined major cardiovascular end points. The choice of first ...

Anti Cancer Drugs Used for Targeted Therapy

A primary goal of targeted therapy is to fight cancer cells with more precision and potentially fewer side effects. For this reason it is a promising therapy for the 3rd millennium1. Traditional cytotoxic chemotherapy works primarily through the inhibition of cell division. In addition to cancer cells, other rapidly dividing cells (e.g. hair, gastrointestinal epithelium, bone marrow) are affect...

Bifunctional phenolic-choline conjugates as anti-oxidants and acetylcholinesterase inhibitors.

Because of the complex cascade of molecular events that can occur in the brain of an Alzheimer's disease (AD) patient, the therapy of this neurodegenerative disease seems more likely to be achieved by multifunctional drugs. Herein, a new series of dual-targeting ligands have been developed and in vitro bioevaluated. Their architecture is based on conjugating the acetylcholinesterase inhibition ...